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Dermoscopy of eccrine angiomatous hamartoma: The spitzoid pattern

Open AccessPublished:September 18, 2018DOI:https://doi.org/10.1016/j.jdcr.2018.06.026

      Key words

      Abbreviation used:

      EAH (eccrine angiomatous hamartoma)

      Clinical presentation

      A 5-year old girl presented with an erythematous, asymptomatic nodule of the left knee, which appeared 1 year before (Fig 1).
      Figure thumbnail gr1
      Fig 1Clinical examination found an erythematous dome-shaped nodule of the left knee.

      Dermoscopic appearance

      Dermoscopic examination found a spitzoid pattern, with brown globules, a background of erythema, and a pseudo-reticular depigmentation around the globules (Fig 2). The lesion was excised to rule out a spitzoid melanoma.
      Figure thumbnail gr2
      Fig 2Dermoscopy shows a spitzoid pattern, with light to dark-brown globules, a background of milky-red erythema, and a pseudo-reticular depigmentation (inversed network) around the globules.

      Histologic diagnosis

      Histologic examination found in the reticular dermis an increased number of eccrine glands and terminal hair follicles admixed with irregular, dilated blood structures and fat lobules (Fig 3). Pathologic features were consistent with the diagnosis of eccrine angiomatous hamartoma (EAH).
      EAH is a rare variety of hamartoma. EAH presents at birth or early childhood as a nonspecific red, brown, or yellow nodule or plaque. When symptomatic, EAH may be associated with hyperhidrosis or pain.
      • Sanusi T.
      • Li Y.
      • Sun L.
      • Wang C.
      • Zhou Y.
      • Huang C.
      Eccrine angiomatous hamartoma: a clinicopathological study of 26 cases.
      The diagnosis is established by histopathology. Recently, the first dermoscopic description of EAH was reported as the popcorn pattern, consisting of multiple yellow, confluent nodules in a popcorn shape, over a background of erythema and linear and arborizing blood vessels.
      • García-García S.C.
      • Saeb-Lima M.
      • Villarreal-Martínez A.
      • et al.
      Dermoscopy of eccrine angiomatous hamartoma: the popcorn pattern.
      Here we report a typical case of EAH, with a spitzoid dermoscopic pattern. The presence of brown globules in dermoscopy is usually indicative of a melanocytic lesion, but in this case it is possible that the globules reflected the numerous dilated eccrine glands. The dermoscopic aspect of EAH is heterogeneous and can be misleading. More cases are needed to describe the dermoscopic landscape of EAH.
      Figure thumbnail gr3
      Fig 3The sections show increased numbers of eccrine glands and terminal hair follicles associated with abnormally dilated vessels (Hematoxylin-eosin saffron stain; original magnification per scale bar).

      References

        • Sanusi T.
        • Li Y.
        • Sun L.
        • Wang C.
        • Zhou Y.
        • Huang C.
        Eccrine angiomatous hamartoma: a clinicopathological study of 26 cases.
        Dermatology. 2015; 231: 63-69
        • García-García S.C.
        • Saeb-Lima M.
        • Villarreal-Martínez A.
        • et al.
        Dermoscopy of eccrine angiomatous hamartoma: the popcorn pattern.
        JAAD Case Rep. 2018; 4: 165-167